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Posts Categorised: Progesterone Therapy

Bio identical Hormone therapy  is the best choice for menopausal women who need hormone replacement therapy because of hot flushes, pain, mood swings etc… One of the most vital roles of Natural progesterone is to balance or oppose the excess of estrogen produced by the body. Many studies demonstrate that unopposed estrogen increases considerably the risk for breast cancer and uterine cancers.

Estrogen levels of women facing menopause drop to forty-sixty%, just enough to stop the menstrual cycle.  However, progesterone levels may drop to close to zero in some women.  Since, progesterone is the precursor to many steroid hormones, one can appreciate just how wide ranging the effects of progesterone deficiency are.

Proper supplementation with Natural progesterone will greatly enhance your overall hormone balance after menopause.

Some other benefits of Progesterone:

  • Stimulates bone-building and helps shield against osteoporosis
  • Boosts the immune system
  • Increases one’s physical and mental energy
  • Makes one calmer
  • Protects against toxic substances and acts as a natural diuretic.

========>> Click here to learn more about Bio identical Hormone therapy and how it can greatly enhance your general health and protect you from unnecessary life threatening conditions
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Progesterone vs Progestins

Natural Progesterone is much safer to use than progestin or progestogens like Provera, Premarin ..etc, because it is  natural to the body and it has no undesirable effects when used as directed. If you have some doubts about how different progesterone is from the progestin, bear in mind that the placenta produces three hundred-400 mg of progesterone daily throughout the last few months of pregnancy.  We understand how safe Natural progesterone is when such level are produced for the developing baby.  However, even a fraction of this dose of Progestin, can cause birth defects.

The progestin used in contraceptive pills and HRT can cause various complications on the long terms such as  loss of vision, breast cancer, an increased risk of strokes, fluid retention, migraine headaches, asthma, cardiac irregularities and depression.

What is estrogen Dominance?

Dr.John Lee (M.D)  used the term “estrogen dominance,” to explain what happens when the ratio or balance of estrogen to progesterone is changed by excess estrogen or inadequate progesterone.

Estrogen is a potentially dangerous hormone when not balanced by adequate progesterone. Both women who have suffered from PMS and women, who have suffered from menopausal symptoms, can recognize the hallmark symptoms of estrogen dominance: weight gain, bloating, mood swings, irritability, tender breasts, headaches, fatigue, depression, hypoglycemia, uterine fibroids, endometriosis, and fibrocystic breasts.  Estrogen dominance is understood to cause and/or contribute to cancer of the breast, ovary, endometrium (uterus), and prostate.

Why Bio identical Hormone therapy is not commonly prescribed?

As Natural Progesterone cannot be patented – it equals NO PROFITS for the pharmaceutical lab.   So, a  majority of doctors have not heard about the benefits of progesterone and the concept of progesterone balance. Fortunately, however, a few enlightened medical doctors in the USA, Britain and elsewhere have been using progesterone to treat their patients for more than 50 years.

========>> Click here to learn more about Bio identical Hormone therapy and how it can greatly enhance your general health and protect you from unnecessary life threatening conditionss

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The NEW SCIENTIST article published in 19 Jan 2002 stated:

“Locked inside our brain is the most powerful sedative, anti-anxiety drug and painkiller all rolled into one. This magical compound derives from the hormone PROGESTERONE …”

Researchers have found that it is the breakdown products of progesterone that have such a potent anaesthetic and analgesic effect. “During pregnancy, for example, as a woman comes close to term, the levels of these breakdown products of progesterone are extremely high”, says Jeremy Lambert, a neuropharmacologist at the University of Dundee.

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Only the natural hormone will do this, the synthetic compounds used in the contraceptive pill, etc. do not work in the same way.

Fortunately, this natural analgesic and anxiolytic is not exclusive to women. There are enzymes in the brain and spinal cord of both men and women that produce similar breakdown compounds of progesterone, known as neurosteroids, and they may act as analgesics, anticonvulsants and even anaesthetics……”

Progesterone against Panic Attack is a Natural Treatment of Anxiety

Progesterone is considered to be a neurosteroid because it affects the mood and behaviour of a person. It is a complex production of chemicals inside the central nervous system which consequently affects how nerves function all over the body.

Progesterone is also found to improve the quality of GABA’s calming effects and repress the excitatory glutamate response. A calming effect is usually noticed and felt within 3-10 minutes after progesterone treatment, either by injection or topical, has been administered.

  • The response of progesterone as an anti-anxiety treatment is similar to that of benzodiazepine drugs, but with no addictive risks.

Progesterone against panic attacks work by switching on the GABA receptor sites. GABA is a calming neurotransmitter.

Unbalanced blood glucose can result to anxiety and panic attack symptoms. Progesterone can certainly help achieve a stabilised blood glucose level. Oestrogen, however, contributes otherwise to the level of blood glucose.

Anxiety or panic attack is triggered by sudden stress situations. Stress is always present in our daily lives. Using progesterone will balance the blood glucose, and then anxiety can be very much alleviated.

Anxiety Panic Attack Symptoms and their Common Treatments

Benzodiazepine (BZD) is the common drug to treat anxiety, severe anxiety and psychosis. Valium or diazepam is a form of this drug. Occasionally SSRI (selective serotonin reuptake inhibitors) antidepressants are also used.

It is found out, however, that patients with anxiety disorder who are using diazepam on a low dose but for a long period became addicted and dependent to this drug.

Diazepam and other BZDs are usually given orally, but patients who have panic attacks may be given intravenously. This drug is also given to alleviate muscle spasms, anxiety, and seizure. Agitation caused by alcohol withdrawal is better control with the use of BZDs.

  • In addition, also bear in mind that diazepam and BZD drugs can increase aggression, anger, mania and hypomania. It also increases the possibility of suicidal thoughts, anxiety, violence, and schizophrenia. To combine these drugs with alcohol is even more harmful.

When applying Progesterone against panic attack topical medications, a substantial amount of cream should be put on. When you achieve the desired effect then slowly lower the amount until you reach your maintenance dose. This medication has the same effect, but with no harmful side effects, just like many anti-depressants in the market, and yes Prozac included.

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Depression is one of the most prevalent mental diseases today (National Alliance on Mental Illness). Its treatments varies, but one of the most effective ways to treat it is lesser known – Progesterone Therapy. Progesterone and depression are linked together through the activities and processes of enzyme monoamine oxidase inside the body.

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Two Types of Depression

There are two categories to Depression: reactive and endogenous. Stressful events like death, problems with family or loss of job can be the cause of reactive depression. On the other hand, Endogenous depression can arise without any outward reason at all. Endogenous depression is known as clinical depression, and it needs more attention than reactive depression.

Depression occurrences continue to arise among people these days. In fact, statistics for UK, says that 10% of the country’s population were found out to have problems with their mental health. In America, roughly about 17 million among its population are going through different types of depressions.

To this date, no solid research supports the real cause of this mood disorder, but many believe that low levels of progesterone and depression are linked. Many studies also suggest that allergens in food, low level of cholesterol, and hypoglycemia could be large contributing factors to a gloomy disposition in life.

Furthermore, a malfunction in thyroid, a reduced level of serotonin, environmental estrogens, and any stressful event may also cause depression.


  • Progesterone and a balanced nutrition are the most effective way to overcome depression with over 80% success rate. These two, however, are often than not, ignored among natural remedies for depression.
  • Serotonin and dopamine are widely proven to play very important roles in causing and preventing depression. To increase the amount of serotonin in body system means to prevent or treat depression and progesterone is one of the most effective natural remedies to do this.
  • Serotonin and melatonin are considered monoamines together with dopamine, adrenaline, and noradrenaline. Serotonin and melatonin come from the amino acid while phenylalanine and tyrosine are precursors to dopamine, adrenaline, and noradrenaline. A substance that come from amino acid methionine called S-adenosylmethionine (SAMe) has anti-depressive properties, but it is very expensive.
  • There are evidence that methionine, folic acid, and vitamin B12 are effective and affordable natural remedies for depression. These supplements and compounds influence the level of serotonin in the body to prevent or treat mood instability.
  • People with low levels of these B vitamins: 1,3,6,12 and folic acid, higher incidence of hypoglycemia, and an excessive excretion of cortisol are prone to depression.
  • Progesterone and depression are associated with the interaction of the following drugs which cause an imbalance between the monoamines:
  • caffeine
  • contraceptives
  • corticosteroids
  • nicotine

Avoid Post Natal Depression

Post Natal Depression (PND), acute or chronic, occurs to 10% of women after giving birth. PND happens when the placenta has been taken away resulting to a sudden drop of progesterone level. There are even rare cases (0.5%0) that develop to temporary postnatal psychosis among women who gave birth. Luckily, these cases can be cured with the help of progesterone treatment.

There are various mental and physical manifestations connected with depression. Milder problems among women may exhibit these manifestations during PMS and menopausal stages. The most severe, on the other hand, comes out in PMD, pre-menstrual and post-natal psychosis. The second one, in very rare cases, results to infanticide, murder or self-mutilation.

These manifestations can be prevented and cured with progesterone treatment, and the same goes for men regardless of age. It is highly important to maintain an adequate amount of progesterone level in the body that can be very helpful for women during puberty, PMS, and menopausal stages.

Ask your physician to test an underactive thyroid which can also cause depression. If diagnosed, supplemental progesterone together with nutrient-based natural remedies for depression can help increase the metabolism of thyroid.

Nutrients essential on a daily basis to fight depression

  • 15 to 60ml Omega 3 flax oil
  • 50mg zinc (extremely important for PND)
  • 100 to 1000mg niacin (vitamin B3)
  • 100 to 200mg vitamin B6 500mg inositol
  • 500mg choline
  • 1000 to 3000mg vitamin C
  • 10 to 20mg manganese
  • 200mcg chromium picolinate
  • 500-1000mg magnesium
  • 400mcg folic acid
  • 300mcg vitamin B12
  • 500mg-6gm of the amino acid tryptophan which are fundamental to the manufacture of serotonin
  • 500-2gm tyrosine plus phenylalanine 400mg DL for the production of dopamine
  • 500mg methionine
  • 500mg GABA to relax and calm

Check out this website for more helpful tips and guides about Progesterone and depression
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Driving thru the beautiful Karoo…I asked Wray about the fears that hold back women from using progesterone therapy?

Well one is the doctor putting her off it, saying it’s a scam or it doesn’t work or there are no studies…

That is laughable because there are hundreds of them. The other is reading the blogs on the internet, instead of reading the studies done on progesterone, they read the blogs. The blogs are full of people complaining about progesterone because they are all suffering from oestrogens dominant symptoms.

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Oestrogen stimulates progesterone and progesterone stimulates estrogens. So if you use a little bit of progesterone, like the 20 – 40mg a day, which is what people are normally told to use, it’s going to stimulate estrogens. You’re going to get then, estrogens effects which is the typical water retention.
Another one big complaint is weight gain ….”I’ve put on five pounds in two days or something”, that’s water retention. Progesterone cannot cause it; it’s a potent diuretic, so much so that it is now used for Traumatic Brain Injury victims to stop oedema.

The other thing they complain about is the genuine weight gain which is fat weight gain and again you come back to estrogens, because oestrogens is a mitogen, it causes cells to proliferate. Progesterone stops cellular proliferation and it cannot cause weight gain because it cannot make cells, divide and multiply.

Because they are given so little to use, they write negative blogs ..which make women fearful of using progesterone or continuing with it.

You have to use a large amount of progesterone, if you do not want to experience oestrogens dominance symptoms. It’s about 400mg a day or more, that’s if you don’t want to experience any oestrogens dominance symptoms. You’ve got people trying 100mg and they’ve got it, then they move to 150mg and they’ve still get it and they start going up more and more. But it just prolongs the agony.

The symptoms so much depend on how much estrogens you’ve got and how many other things are also affecting you,  such as the foods you eat, your stress levels, it all plays a huge role.

Lack of Vitamin D also affects progesterone, again that was found in the TBI [Traumatic Brain Injury ]studies.

So you can’t think, ‘Let’s try some progesterone.., I’ve heard good reports about it’ and then of course you get bad results because you have not used enough progesterone cream! .

I have been advising using 100 – 200mg a day but if you have severe problems like asthma, seizure or heart problems, all of which can be caused by oestrogen because of it is an inflammatory hormone, you are going to need a lot of progesterone.
But always do it in conjunction with your health practitioner because it’s scary if you suddenly have an asthma attack because you haven’t used enough progesterone. You have to use a lot.

There’s one girl on the wed using 500mg a day. Prior to that she was going up slowly, 150mg, 200mg, 250mg and she was just getting more and more attacks. 500mg she’s had none. So if you’ve got a major problem like that, always do it with somebody who understands. But for minor things like, headaches or bleeding problems, then you can go at it alone if you have to…. it’s always better when you get support, but often that support is just not there!!

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