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Women are hesitant using Bio-identical Progesterone cream when they don't understand the difference between; Progesterone Progestin & Progestogens. Health Professionals often use these definitions interchangeably creating confusion in the mind of the public. Only Bio Identical Progesterone (just as our body makes it) is safe to use. Unlike synthetic hormones, Progesterone can be broken down into metabolites, that will calm us, act as an anti-inflammatory... among many other benefits. Our health choices depend upon understanding the fundamental differences between Progesterone, Progestin and Progestogens....find out more..
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Transcript of the interview:

 Vero:  Another question that we come across often and it’s the misconception or the lack of understanding, even among the medical people, between natural Progesterone or Progesterone Progestin and Progestogens.

 Wray:  Yes. They take progesterone and they change the molecule. The Progestin’s were designed because they discovered that progesterone, when taken orally, was destroyed in the gut and the liver. So, to overcome this so they could add it to the contraceptive pill because they realized both hormones were needed, they came up with the Progestins. They’re many now, some are derived from progesterone, some unfortunately are derived from testosterone, so they have androgenic properties so can cause acne and skin problem and facial hair in women who use them. There are dozens now in the market but in every one of them, the actual progesterone molecule has been changed.

Vero: There are so much adverse effects in regards to Progestins and Progestogens that makes people a bit scared and they don’t understand how safe natural progesterone is because of the adverse effect that they are with Progestin and Progestogen that there’s a bit of mix up and confusion arising from that, isn’t it?

 Wray:  Hugely! I think principally because the papers and doctors use the term interchangeably. Luckily, there are many people who realize and I’ve got papers (medical articles), where they say, not all Progestins are created equal and they compare the natural with the others. I’m glad because, I just wish though, this would get through to the medical profession that they are very, very different substances, very, very different. The one thing they found and this came out through the TBI (traumatic brain injury) studies, is because they tried MPA (Medoxyprogesterone-Acetate) which is commonly known as Provera. They tried that and it does reduce oedema like progesterone does but there it ends. It cannot be metabolized into the same metabolites that I mentioned earlier that progesterone is. So, you won’t get Allopregnanolone, which has this potent analgesic anti-anxiety effect. So, they’re very, very different. The body cannot metabolize it into the metabolites which are also vital. One day, it might get known.

Vero: Is Provera, Premarin are they as widely used today as it was 15 years ago?

 Wray:  No. They did the Women’s Health Initiative and they did this study in England called “The Million Women Study.” The result from that really puzzled people because they found that the things that they thought estrogen was helping for actually became worse. Women heard about this of course, so stopped using it, huge amount. They’re now trying to persuade women to use estrogen only for a shorter period of time and as low a dose as possible to get rid of menopausal symptoms. But, you and I know that progesterone gets rid of them safely without taking the risk of using estrogen. So I don’t see the point of it.
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