Posts Categorised: Natpro Progesterone Cream

 Straight Talks with Wray Whyte…

3 Essentials to look for when buying a Progesterone Cream: Are the ingredients safe? Is the Progesterone well absorbed? What is the amount of active ingredients in the cream?  Look for Natural Preservatives instead of synthetic one  and make sure you are not paying for the price of fancy container but rather for the amount of progesterone in the cream.

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Transcript of the interview

 Vero Laos: The question that many, many people would ask in regards to the choosing the right progesterone cream. There are so many progesterone creams on the market today.

Wray Whyte: I don’t mind what cream or what suppository or however people take it, I mean, I’ll answer any questions. It doesn’t make any difference to me. But what I do ask people to look for is the ingredients, are they safe? Because some of them have got adverse effects and is it absorbed?

We run saliva tests periodically to see if the progesterone is being absorbed. So, a naturopath does it for us, she gets a patient who’s never had it, she does it before test and then a month or two later an after test. The progesterone in every case shoots up. So, it’s absorbed very well.  So, if you use a cream, some people have said they’ve used one which is incredibly thick and takes a long, long time to rub in. That shouldn’t be the case. You shouldn’t have to rub it in a long time. So, you need to look at what carrier, the thickness, the toxic ingredients if there are any. A lot of doctors prefer using injection and suppositories. They also like the oral or the fizzy vaginal tablet because it gives you a dose, they are used to doses. To my mind, progesterone should not be done in dose form. It should be solely by symptom. So, I prefer a cream for that reason.

You don’t have a measured amount.  So, for instance, if somebody’s using suppositories and they want to reduce the amount because their symptoms have gone, what do you do? Shave a bit off the suppository each day to get less progesterone, cut it in half a quarter? The same with injections which are apparently very painful, you could give half an injection I suppose, same with the capsules. In fact, if people are taking capsules, I say, cut it open, add it to a cream and rub it on your skin instead.

The other advantage to cream, it can just be put anywhere. It is the best burn ointment I have ever come across. So, people have used it to heal leg ulcers, just filling up the ulcer with progesterone in places and other minor wounds. You can’t do that with a suppository or an injection. So, I always asked them to look at the ingredients and the amount obviously, if you’re buying something which isn’t as strong because a lot of people look at the price of the container. They don’t look at the fact that they’re actually buying an active ingredient. If they work out a comparison, they’ll find that in some cases, they’re paying twice what they would be paying with another brand. That is the important thing to look at, not the price of the container. So, those are the things I would ask people to look for.

Vero Laos:  You did mention the toxic ingredients that we have to watch out. Can you just expand a bit more on that?

Wray Whyte:  Some of the preservatives they use. The Parabens have been used for years. There have been papers done on them that say they are still safe and some that advice not using them.  The Propyl paraben has got slight estrogenic properties. So, maybe it’s advisable not to use something with that in and another one that people favour is Phenoxyethanol. Its hazard rating isn’t very high but it is a synthetic so I wouldn’t recommend using it. Antioxidants, mostly people use Rosemary or Vitamin E for the antioxidant properties it has. I haven’t yet seen in the progesterone creams, BHA or BHT. Now, those are synthetic antioxidants used in a lot of fried foods and baked foods, biscuits and cookies and things like that but those have got estrogenic properties. But as I‘ve said, I haven’t seen those used in progesterone creams but certainly in other creams. So, look for the natural antioxidants, natural preservatives rather than synthetic.

You know, you’re using a progesterone cream all you actually need is a vehicle which is an oil to get it into the skin. You do not need 20 other ingredients added to it. Just add some cost to the cream. So, that’s one reason why we’ve kept no unnecessary added ingredients. I remember once, you asked me about the liposomes’ and we never got to finish that. I think we got cut off. A lot of creams are saying that they’ve got liposomes in them but it’s a very expensive system for getting drugs into the body. You can put a tiny amount of liposomes into a cream and say its got liposome’s in it. But it won’t be based solely on just liposomes because they’re far too expensive. It will have other oils in it as well. And, from the saliva tests we run, we found they’re not necessary, not at all. Progesterone gets into the tissue. So, it’s an expensive cream which to my mind is not worth bothering with.

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Many women are anxious to know how to use natural progesterone cream correctly. The answers to these 10 most frequently asked questions will remove any confusion and help you get the best results when using progesterone therapy.

These 10 pieces of advice will help stabilize your progesterone levels and deal with unpleasant symptoms.

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1. Where to apply natural progesterone cream?

Choose an area where there are lots of capillaries that are close to the surface of the skin. Absorption is best on skin sites where people blush: face, neck, chest, breasts, inner arms and palms of the hands. The progesterone cream will be quickly absorbed and start circulating in the bloodstream. Avoid putting the cream on the fattiest areas of the body, as this may inhibit absorption as the fat areas will store the progesterone. Moreover rotate the sites where you apply the cream each time you use it to avoid saturation.

2. How often should I use progesterone cream?

Split dosage and apply the cream once in the morning and once in the evening before bed. Using it before bedtime may help some people to sleep better. Splitting the dosage up ensures 8-12 hours of sustained delivery. If you apply it all at one time, only once a day, it will still only last 8-12 hours, leaving the other 12 hours where you are not receiving any. The split dosage ensures optimum progesterone levels are maintained.

3. Why do I feel worse when using natural progesterone cream?

When using progesterone cream for the 1st time after a long period of progesterone deficiency, the estrogen receptor sites will be stimulated, for a short period of time. This might increase the estrogen dominance symptoms such as breast tenderness and swelling, spotting, fluid retention, dizziness, hot flashes, fatigue, headaches and nausea. It can be annoying, but be re-assured that it will go away over the next couple of cycles, as progesterone levels increase.

4. What is the recommended progesterone cream dosage?

As far as the dose is concerned, it really depends on symptoms. It doesn’t depend on weight, age, height. It does depend a bit on sex because a man doesn’t need as much. Most women are advised to use 20 to 40 milligrams a day to use but we would say to use 100mg to 200mg or more according to the intensity of the symptoms.

5. What time of the month should I apply progesterone cream?

All women, irrespective of the length of their cycle, should start ovulating 14 days before they start bleeding again. This means that you should start using the cream at ovulation, if you know when that is, or 14 days before your next period is due to. If you don’t ovulate or have a period, stick to the 28-day cycle, choosing any day to start.
A 21-day cycle – ovulation should occur on day 7
A 28-day cycle – ovulation should occur on day 14
A 36-day cycle – Ovulation should occur on day 21
Most websites and books advise starting the cream on day 14, this is entirely incorrect! The cream should only be used from ovulation, for the last 14 days of the cycle

6. Can I use the cream continuously?

If somebody is pre-menopausal, i.e. they got a regular cycle, but are having horrific symptoms, I tell them to ignore the cycle. So in other words, they would use the cream every day and through their period as well for two to three months. Sometimes they require longer, sometimes shorter but it doesn’t harm to use it through the cycle. It gives progesterone a chance to become dominant. If you take a break, estrogen can rise so you’re back to square one every time you start the progesterone. Your period will sort itself out again once you start following the cycle

7. How much Progesterone cream to use?

All the successful studies done on progesterone indicate between 100-200mg should be used each day. This equates to 3-6ml of a 3.33% concentration cream (such as Natpro) per day. Some studies are used 400-600mg/day. As much as 1200mg per day is used on patients suffering Traumatic Brain Injury (TBI). The late Dr Catherine Dalton used to give her patients suffering from psychosis 2400mg per day and 800mg for nausea.

8. Which Progesterone Cream should I buy?

Not all creams are created equals and there are 3 essentials to look for when buying a Progesterone Cream: Are the ingredients safe? Is the Progesterone well absorbed? What is a number of active ingredients in the cream? Look for Natural Preservatives instead of synthetic one and make sure you are not paying for the price of a fancy container but rather for the amount of progesterone in the cream.

9. When to stop using natural progesterone cream if pregnant?

If you are trying to get pregnant while using natural progesterone cream, continue using the cream until you are sure that you are not pregnant. If you get a positive pregnancy test result, continue on with the progesterone cream. Be sure not to skip a day of use of NPC in pregnancy. Doing so may result in a sudden drop of progesterone levels, which may cause miscarriage. Have two bottles on hand at all times to ensure you don’t run out.

10. How to Reduce the amount of cream?

Reduce the amount ONLY when you feel stable enough to do so. It is vital to do it SLOWLY – if done too quickly your symptoms will come back . If it happens, just increase the amount of cream until you feel stable again and then slowly try again reducing. This should be done over a few weeks to prevent unpleasant symptoms returning. Do not reduce by more than 16-20mg at a time. Stay on the reduced amount for a few days before reducing again. Continue reducing until you find a level that suits you. Symptoms will return if you reduce by too much and too quickly. Never reduce to less than 100mg/3ml per day as all adverse symptoms will return.

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Natpro Progesterone Cream has just launched its new Airless container. The main benefit of this Progesterone airless dispenser is that each pump action [squirt] provides the exact amount of cream you desire for every application. It is also completely air tight and is resistant to sun damage. Every last drop is used up as NO residue leftover in the pump!
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How many Natpro cream squirts do I need?

As previously discussed on this blog, the amount of progesterone cream needed does not depend on age, weight or height, but rather on the severity of the estrogen dominance symptoms experienced. The dosage of progesterone is always worked out according to the severity these symptoms. The aim in using a bio-identical progesterone cream is to restore a proper progesterone to estrogen ratio. When you reach a proper ratio, the estrogen dominance symptoms will subside and be replaced with a feelling of well being.

As a general guideline of use:
for mild symptoms: 100-200mg/day of progesterone is sufficient.
If symptoms are severe, then 400-500mg/day is advised.

Each pump action provides 1.5 mls per squirt. According to your personal need, you can work out how many squirts you will require in the morning, as well as in the evening.
One other great benefit about the Natpro airless pumps is that “No residue remains in these containers when empty”.

This table below will help you work out how many squirts you need.

Is the Natpro Airless Dispenser more expensive than the Natpro tubes?
The price will remain essentially the same per any given weight/volume of cream.

Price of Natpro Tubes – 60mls

Price of Natpro dispensers – 100mls

What do I get when I order Natpro progesterone cream air pump?

‌ Each dispenser contains 100 grams (3.5 oz) of cream and 3,333mg progesterone.
(Natpro cream has a concentration of 3.33% progesterone or 33.33 milligrams per gram)
‌ Each pump comes with a full instructional pamphlet

  • The ingredients of each dispenser:
    de-ionised water
    caprylic/capric triglyceride
    cetearyl olivate/sorbitan olivate
    progesterone Ph. Eur. USP. JP.
    Aspen bark extract
    dehydroxanthan gum
    vitamin E
    Natpro has an unopened shelf life of 18 months

How does Natpro airless pump work?

The innovative technology of a airless pump uses the concept of vacuum & piston to release its contents. Unlike the traditional style pump & straw which pushes air into the container to force product outward. When the pump is pushed, a piston on the bottom of the container presses the product upward and out of the opening.

Where to Apply Natpro progesterone cream

The topical cream is absorbed very well anywhere on the body. It does not have to be applied to the thin areas of the skin only. Amazingly hair follicles absorb progesterone as well. The skin comprises of 95% kerotinocytes loaded with progesterone receptor sites.
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Great Testimonial from Connie – She has just been using Natpro Progesterone Cream only for 4 months!! Amazing how it cleared so many of her  symptoms.  No wonder that Progesterone is called the “mother of all hormones” – Progesterone is the hormone from which every other hormone in our body is made….
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This is the best product on the market. I do not EVER want to be without it. I have read a lot of information about progesterone deficiencies, and found out that is what I have experienced for many years. I wish I would have known this a long time ago. It would have saved me years of frustration!
I was experiencing frequent UTI’s. I found immediate relief after using Natpro the first time. I have not had one since I started using Natpro 4 months ago.
It also helped stop depression, increased my energy and libido.
I was also so cold all the time, I couldn’t stand to be out in the cold.
After using Natpro, I do not feel cold and can tolerate being outdoors in winter.
I have had a goiter on my thyroid for many years. My doctor started me on thyroid medication. The goiter only went down a small amount. I was also having symptoms of Hashimoto’s disease. After reading about the association of hypothyroid and low progesterone, I started massaging Natpro directly onto my thyroid gland at the base of my neck. Within one week the goiter is nearly gone!!

Also the thyroid levels are normal again.

Thanks so much for your persistence in getting this info to other women. It has helped me tremendously.
I tell any woman that will listen.


Connie Tate-Wiggins

“Progesterone is an Essential Raw Material from which our body makes many of the other Hormones Vital for Good Health”

It’s this simple fact that helps anyone appreciate just how wide ranging the effects of a deficiency can be. This is why progesterone therapy can be effective in treating such a wide range of health problems, from…

  • post natal psychosis, to
  • traumatic brain injury (TBI)
  • myopathy
  • peripheral neuropathy
  • pregnancy problems such as miscarriages and pre-term births
  • cancer
  • sleep
  • anxiety and stress
  • Hot Flushes
  • neuro-degeneration
  • PCOS
  • benign prostate hyperplasia
  • ‘man boobs’
  • acne
  • endometriosis
  • fibroids
  • peri-menopause
  • menopause
  • miscarriage
  • candida
  • migraines

…and many more.
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Natpro Content –

Natpro contains only vegetable substances. No animal has suffered or will ever suffer because of its production or use.

Natpro progesterone cream does not contain any toxic substances – such as growth hormones – found in today’s animal products. You are protected!

The formulation for Natpro progesterone cream has remained almost unchanged since it was originally developed in the years 1996/7. Well, that’s now changed.
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The pursuit of an organic natural progesterone cream that is free of both “parabens” and “PEG” has long remained my dream and its now been realized. It’s taken a long time coming and I’ll make no secret of the fact that the path has lead down many blind allies and hit many obstacles. The real difficulty has been in getting a “paraben free” preservative system that doesn’t simply substitute another “unnatural” ingredient.

What’s wrong with parabens?

There are relatively rare documented instances where parabens have been found to cause skin irritation, contact dermatitis, or allergic skin reactions. They are considered to be of low irritation potential compared with many other preservatives. Although there is no evidence that any cosmetics containing parabens pose a health risk they can, however, cause reactions in individuals with paraben allergies. Only a tiny percentage of the general population are allergic to parabens. Some studies have led to concerns over their continued use, and there is currently a shift away from them. This is despite the rejection of the breast cancer tissue study by the majority of the scientific community, and the extremely weak estrogenic effect found for butylparaben (no effect was seen with methyl or propyl parabens previously used in Natpro).

Despite this, my attitude has been… “why take any risk when it can be avoided?”

Most organic preservatives simply can’t stand up to the rigorous “challenge testing” required to meet the necessarily high standards to ensure aqueous creams avoid becoming breeding grounds for toxic moulds and bacteria. There are many organic preservatives out there that are touted as doing the job. The truth is they simply don’t do a good enough job without “support” from conventional preservatives such as the parabens. Take the much publicized “grapefruit seed extract”… it simply can’t work alone.

Natpro’s new system works.

It has undergone rigorous challenge testing. But that’s not all that’s different. We’ve also changed (again after much painstaking research) the emulsifying agents to a completelyPEG free combination.

What’s “PEG” mean?

Well, its shorthand for ‘polyethylene glycol’. It’s found in many formulas and has been causing some concern in recent times as a potential health hazard. Although this is far from proven I decided to act now rather than later so we developed an alternative system that is entirely “PEG free”.

The new Natpro progesterone cream formula is about as natural as you can get.

I’m also particularly pleased because its “emolience” or “feel quality” is, if anything, an improvement on the old formula.

But perhaps most important of all

…its functional ability to ensure the efficient transdermal delivery of the progesterone itself is second to none. This has been established through rigorous, repeated saliva testing.

What do I get when I order Natpro progesterone cream?

Each tube contains 60 grams (2 oz) of cream and 2,000mg progesterone
Natpro cream has a concentration of 3.33% progesterone or 33.33 milligrams per gram
Each tube comes with a full instructional pamphlet
Each tube contains :

  •         de-ionised water
  •         caprylic/capric triglyceride
  •         cetearyl olivate/sorbitan olivate
  •         progesterone Ph. Eur. USP. JP.
  •         Aspen bark extract
  •         dehydroxanthan gum
  •         vitamin E

Natpro has an unopened shelf life of 18 months

The Content in more details:

  • The progesterone in Natpro is identical to the progesterone your body makes. ‘Progesterone Ph. Eur. USP JP’ is derived principally from stigmasterol, a steroidal sapogenin. Phytosterols are chemically similar to cholesterol which is found in animals. Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone they are used as starting points for the synthesis of progesterone. In the southern United States the sweet potato (Ipomoea batatas) is called a yam, as are some edible members of the aroids. These plants do not contain any sapogenins. Don’t confuse Natpro progesterone cream with a bean or yam “extract”. Such extracts do not contain progesterone.
  • caprylic/capric triglyceride – is a ‘medium chain’ triglyceride of fractionated vegetable fatty acids extracted from coconut oil. It is colourless, neutral in odour and taste and has a very low viscosity. It has very good resistance to oxidation. It is an ideal ‘carrier’ for progesterone, as it penetrates the skin readily and is easily absorbed. It does not leave a greasy film and helps to retain moisture. Very importantly… it’s not a mineral oil and is unrefined.

Let’s examine these points more closely:

    • Mineral oils, being petro-chemicals, are potentially harmful because they are “endochrine disruptors”. They rob your body of the oil soluble vitamins A, D, E & K , and so deprive you of vital nutrients. Never use any product on your skin that contains mineral oils.
    • Heating or refining any vegetable oil causes damage. The good “cis” fatty acids that are found in vegetable oils are turned into bad “trans” fatty acids and the result is highly carcinogenic. Don’t use refined oils.
  • Vitamin E (dl-alpha tocopherol) – All emulsions made with vegetable oils have the potential to go rancid. For this reason dl-alpha tocopherol is used as it’s an ‘in vitro’ antioxidant. Standard preparations contain only 0.1%, however, Natpro progesterone cream contains a further 0.2%.
  • The new two part emulsifier systemcetearyl olivate/sorbitan olivate – a unique natural PEG-free organic emulsifier from Olive oil. It reduces skin water loss, has a high moisturizing effect, is hypoallergenic and biomimics the skin.
  • The new natural preservative systemAspen bark extract – is a natural organic preservative and as such is a unique discovery as it is an effective natural replacement for commonly used harmful chemical preservatives such as the ‘parabens’. It also improves the emollience (the ‘feel good’ factor) of the cream.
  • de-ionized water this is a pure pharmaceutical grade standard

When do I use Natpro progesterone cream?

How much Natpro do I use?

How do I apply Natpro?

Full instructions – regardless of your condition, symptoms, disease, sex or age – are provided with each set of Natpro

What else do I get when I order Natpro progesterone cream?

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