Posts Categorised: Progesterone

A few years ago, Dr Mercola stated that constant use of progesterone can cause ‘dermal fatigue’ – Dermal fatigue basically is a condition when the body’s adipose tissues undergo a process of saturation up till a point when further absorption is reduced.

He said: “Progesterone is highly a fat soluble hormone. After many applications, the fat tissue becomes saturated with the hormone and it does not provide any beneficial effects. After reaching the saturation point, progesterone may hamper the adrenal hormone, cortisol and testosterone.”

However, This Claim Is Not Substantiated

If it was so, overweight people who have been using progesterone for a long period, would be saturated with progesterone and could go a long way without applying the cream, considering the amount of progesterone stored in their body!
But this is not the case, because the estrogen dominance symptoms would return quite quickly after stopping the use of progesterone. Progesterone levels begin dropping in the blood after about 13 hours, necessitating using it at least twice a day.

Progesterone Doesn’t Just ‘Get Stuck’ In Your Fat Tissues

Both Progesterone and Vitamin D are made from cholesterol, both these molecules are very similar. Not only is Vitamin D fat soluble but it can also be converted into a steroid. Moreover, just like progesterone, Vitamin D can also be transported throughout the body from the skin.

Yes, it does enter the fat cells, as it’s not water soluble, but the fat contains capillaries and they have red blood cells in them. These red blood cells are responsible for picking up and distributing the progesterone to the other tissues present in the body.

Check this article in the ‘Menopause Journal’ –  It says “However, one explanation is that after absorption through the skin, the lipophilic ingredients of creams, including progesterone, may have a preference for saturating the fatty layer below the dermis. Because there appears to be rapid uptake and release of steroids by red blood cells passing through capillaries, these cells may play an important role in transporting progesterone to salivary glands and other tissues.”, in other words saturated or not it still gets around the body.

But to remove it from your system, it does not require as much as 2 years either. Levels begin dropping after about 13 hours, necessitating using 100mgr to 200mgr of progesterone at least twice a day to reverse your symptoms.

Find out if you have Dermal fatigue

One way of finding out if you have dermal fatigue, is to drastically drop your progesterone intake for a few days, before increasing it again
If you experience oestrogen symptoms during that gap, you can be reassured that her receptors were working fine and that you do not have ‘Dermal fatigue’.

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Many women use progesterone cream to reverse or neutralize estrogen dominance symptoms. These estrogen dominance symptoms are essentially caused by toxic chemicals in the environment which mimic the actions of estrogen in our body – They become toxic xeno estrogen to our body, xeno meaning foreign. When the symptoms of estrogen dominance reduce, many menstruating women stop using the cream. Although, it is still recommended to use the cream in small dosages since it has help balance progesterone to estrogen ratio and has anticancer properties.

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The Dangers of Our Toxic World for Our Hormonal Health

In more than 5 decades, the world has changed rapidly and this affected our environment quite negatively. We can no longer keep up with the radical changes in our surrounding, especially to the toxin footprints of man-made chemicals. Below are just some of the samples of how our environment today affects the general health of people all over the world:

  • In 1920s, cancers can only be found to 3% of the population, but it rapidly increased to 40% among today’s population. Deaths caused by cancers are also alarming in the past years.
  • Allergies are more prevalent today. This can be observed with our kids who have to carry asthma pumps when on the playground.
  • Many children today are also diagnosed with ADD and ADHD. Many of them are treated with Ritalin, a stimulant which can seriously trigger mental health problems later on in their lives.
  • Today’s records show that heart diseases can cause death among people in their 30s.
  • Infertility hinders population increase in the West as their sperm counts are down by 50%.
  • Depression now occurs globally among men and women, whether they are young or adult.
  • Osteoporosis is even present with young males today.

6 Most common Chemicals that creates toxic xeno estrogens in our body

  • Petro-chemicals are toxic xeno-estrogens which can be found on vaseline based skin creams, common detergents, wax floor polish and paints. These chemicals are also present in car immisions, which mean that we are exposed to it when we use our cars, walking along the road, or by just having a coffee outside of the shop.
  • Synthetic Hormones and estrogenic compounds can be acquired by eating meat. Cattles are fed with D.E.S. (diethol stilbestrol) hormone to fatten them quickly. Chickens, on the other hands, are fed with hormone-filled food to make them grow fast.
  • Pesticides with DDT and DDE. These highly toxic home and garden instruments are still widely used in Africa and other 3rd world countries. Furthermore, other herbicides and pesticides have dieldrin, toxaphene, mirex, heptachlor and kepone. These chemicals are capable of imitating natural estrogen.
  • Polycarbonated plastics. These toxins are present in baby bottles, water jugs, cling wrap and polystyrene to name a few. Plastics can be found practically anywhere.
  • Polychlorinated biphenyls (PCBs). If you are using any electronic device, then you’re exposed to these chemicals. These are widely used in electronics industry.
  • Synthetic man-made estrogen drugs. Drug companies incorporate them to produce contraceptive pill and HRT. Ironically, these are even advertised as something that can save lives and good for our health.

Only progesterone protects from estrogen created from toxic chemicals found in our today’s environment.

Progesterone Protects from Oestrogen Created by the Chemical Revolution

Man made synthetic chemicals are known not only to cause damages in our environment, but also directly to our health. Endoctrine Disruptors are a major factor in hormonal imbalances. Whereas xeno-estrogens immitates the natural estrogen, thus, the imbalance between estrogen and progesterone levels.

There are currently 51 toxic chemicals identified as hormone disrupters causing health imbalances. For one, xeno-estrogens are present in the food that we usually eat. They exist in the animal fat and the moment we ate these animals, we acquire them in our fats, too.

Xeno-estrogens can disrupt the functions of the body by putting estrogen receptors to the cells. These cells will not be able to interact well with the body organs and systems, which will then lead to malfunctions of the body.

The use of bio-identical progesterone is the best way to keep estrogens level under control. As with the presence of toxic xeno estrogens from our toxic enviromment, the progesterone to estrogens ratio becomes imbalanced . This condition will lead to what is called estrogen dominance sumptoms, where the balance of progesterone and estrogen inside the body is affected.

Only Progesterone Therapy Reverses Estrogen Dominance Symptoms

It’s a fact that our grandparents didn’t need any progesterone therapy in their younger years because of their environment’s condition. This, however, is no longer the case today since we are exposed everyday to endocrine disruptors (xeno estrogens) found in our environment.

These days, many people experience all-time high stress levels, which cause health complications. Not to mention that progesterone levels are being drained by any sort of stress. Progesterone hormones are vital to keep the balance of our mental, emotional, and physical conditions. After all, progesterone is called the “Mother Hormone” for nothing. It is actually where many other hormones in our body are derived; these include stress and sex hormones.

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The NEW SCIENTIST article published in 19 Jan 2002 stated:

“Locked inside our brain is the most powerful sedative, anti-anxiety drug and painkiller all rolled into one. This magical compound derives from the hormone PROGESTERONE …”

Researchers have found that it is the breakdown products of progesterone that have such a potent anaesthetic and analgesic effect. “During pregnancy, for example, as a woman comes close to term, the levels of these breakdown products of progesterone are extremely high”, says Jeremy Lambert, a neuropharmacologist at the University of Dundee.

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Only the natural hormone will do this, the synthetic compounds used in the contraceptive pill, etc. do not work in the same way.

Fortunately, this natural analgesic and anxiolytic is not exclusive to women. There are enzymes in the brain and spinal cord of both men and women that produce similar breakdown compounds of progesterone, known as neurosteroids, and they may act as analgesics, anticonvulsants and even anaesthetics……”

Progesterone against Panic Attack is a Natural Treatment of Anxiety

Progesterone is considered to be a neurosteroid because it affects the mood and behaviour of a person. It is a complex production of chemicals inside the central nervous system which consequently affects how nerves function all over the body.

Progesterone is also found to improve the quality of GABA’s calming effects and repress the excitatory glutamate response. A calming effect is usually noticed and felt within 3-10 minutes after progesterone treatment, either by injection or topical, has been administered.

  • The response of progesterone as an anti-anxiety treatment is similar to that of benzodiazepine drugs, but with no addictive risks.

Progesterone against panic attacks work by switching on the GABA receptor sites. GABA is a calming neurotransmitter.

Unbalanced blood glucose can result to anxiety and panic attack symptoms. Progesterone can certainly help achieve a stabilised blood glucose level. Oestrogen, however, contributes otherwise to the level of blood glucose.

Anxiety or panic attack is triggered by sudden stress situations. Stress is always present in our daily lives. Using progesterone will balance the blood glucose, and then anxiety can be very much alleviated.

Anxiety Panic Attack Symptoms and their Common Treatments

Benzodiazepine (BZD) is the common drug to treat anxiety, severe anxiety and psychosis. Valium or diazepam is a form of this drug. Occasionally SSRI (selective serotonin reuptake inhibitors) antidepressants are also used.

It is found out, however, that patients with anxiety disorder who are using diazepam on a low dose but for a long period became addicted and dependent to this drug.

Diazepam and other BZDs are usually given orally, but patients who have panic attacks may be given intravenously. This drug is also given to alleviate muscle spasms, anxiety, and seizure. Agitation caused by alcohol withdrawal is better control with the use of BZDs.

  • In addition, also bear in mind that diazepam and BZD drugs can increase aggression, anger, mania and hypomania. It also increases the possibility of suicidal thoughts, anxiety, violence, and schizophrenia. To combine these drugs with alcohol is even more harmful.

When applying Progesterone against panic attack topical medications, a substantial amount of cream should be put on. When you achieve the desired effect then slowly lower the amount until you reach your maintenance dose. This medication has the same effect, but with no harmful side effects, just like many anti-depressants in the market, and yes Prozac included.

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