Natpro Content

‌  Natpro cream dispenser content

• Each dispenser contains 100 grams (3.5 oz) of cream
• See here for recommended usage levels
• Natpro cream has a concentration of 3.33% progesterone or 33.33 milligrams per gram
• Each dispenser comes with a full instructional pamphlet
• Each dispenser contains :
de-ionised water
caprylic/capric triglyceride
cetearyl olivate/sorbitan olivate
progesterone Ph. Eur. USP. JP.
Aspen bark extract
dehydroxanthan gum
vitamin E
• Natpro has an unopened shelf life of 18 months

‌‌‌   Natpro Tubes cream content

The Natpro Tube has the same content and concentration as the airless pump, however
• Each tube contains 60 grams (2 oz) of cream and 2,000mg progesterone

Natpro contains only vegetable substances. No animal has suffered or will ever suffer because of its production or use. Natpro progesterone cream does not contain any toxic substances – such as growth hormones – found in today’s animal products. You are protected.

Here’s a note on recent changes made to Natpro’s formula…
The formulation for Natpro progesterone cream has remained almost unchanged since it was originally developed in the years 1996/7. Well, that’s now changed.


The pursuit of an organic natural progesterone cream that is free of both “parabens” and “PEG” has long remained my dream and its now been realized. Its taken a long time coming and I’ll make no secret of the fact that the path has lead down many blind allies and hit many obstacles. The real difficulty has been in getting a “paraben free” preservative system that doesn’t simply substitute another “unnatural” ingredient.

What’s wrong with parabens?

There are relatively rare documented instances where parabens have been found to cause skin irritation, contact dermatitis, or allergic skin reactions. They are considered to be of low irritation potential compared with many other preservatives. Although there is no evidence that any cosmetics containing parabens pose a health risk they can, however, cause reactions in individuals with paraben allergies. Only a tiny percentage of the general population are allergic to parabens. Some studies have led to concerns over their continued use, and there is currently a shift away from them. This is despite the rejection of the breast cancer tissue study by the majority of the scientific community, and the extremely weak estrogenic effect found for butylparaben (no effect was seen with methyl or propyl parabens previously used in Natpro).

Despite this, my attitude has been… “why take any risk when it can be avoided?”

Most organic preservatives simply can’t stand up to the rigorous “challenge testing” required to meet the necessarily high standards to ensure aqueous creams avoid becoming breeding grounds for toxic moulds and bacteria. There are many organic preservatives out there that are touted as doing the job. The truth is they simply don’t do a good enough job without “support” from conventional preservatives such as the parabens. Take the much publicized “grapefruit seed extract”… it simply can’t work alone.

Natpro’s new system works.

It has undergone rigorous challenge testing. But that’s not all that’s different. We’ve also changed (again after much painstaking research) the emulsifying agents to a completely “PEG free” combination.

What’s “PEG” mean?

Well, its shorthand for ‘polyethylene glycol’. Its found in many formulas and has been causing some concern in recent times as a potential health hazard. Although this is far from proven I decided to act now rather than later so we developed an alternative system that is entirely “PEG free”.

The new Natpro progesterone cream formula is about as natural as you can get. I’m also particularly pleased because its “emolience” or “feel quality” is, if anything, an improvement on the old formula. But perhaps most important of all… …its functional ability to ensure the efficient transdermal delivery of the progesterone itself is second to none. This has been established through rigorous, repeated saliva testing.

Lets look at the contents in more detail :

• The progesterone in Natpro is identical to the progesterone your body makes. ‘Progesterone Ph. Eur. USP JP’ is derived principally from stigmasterol, a steroidal sapogenin. Phytosterols are chemically similar to cholesterol which is found in animals. Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone they are used as starting points for the synthesis of progesterone. In the southern United States the sweet potato (Ipomoea batatas) is called a yam, as are some edible members of the aroids. These plants do not contain any sapogenins.

Don’t confuse Natpro progesterone cream with a bean or yam “extract”. Such extracts do not contain progesterone.

caprylic/capric triglyceride – is a ‘medium chain’ triglyceride of fractionated vegetable fatty acids extracted from coconut oil. It is colourless, neutral in odour and taste and has a very low viscosity. It has very good resistance to oxidation. It is an ideal ‘carrier’ for progesterone, as it penetrates the skin readily and is easily absorbed. It does not leave a greasy film and helps to retain moisture. Very importantly… it’s not a mineral oil and is unrefined.
Lets examine these points more closely:
o Mineral oils, being petro-chemicals, are potentially harmful because they are “endochrine disruptors”. They rob your body of the oil soluble vitamins A, D, E & K , and so deprive you of vital nutrients. Never use any product on your skin that contains mineral oils.
o Heating or refining any vegetable oil causes damage. The good “cis” fatty acids that are found in vegetable oils are turned into bad “trans” fatty acids and the result is highly carcinogenic. Don’t use refined oils.

Vitamin E (dl-alpha tocopherol) – All emulsions made with vegetable oils have the potential to go rancid. For this reason dl-alpha tocopherol is used as it’s an ‘in vitro’ antioxidant. Standard preparations contain only 0.1%, however, Natpro progesterone cream contains a further 0.2%.

The new two part emulsifier system… cetearyl olivate/sorbitan olivate – a unique natural PEG-free organic emulsifier from Olive oil. It reduces skin water loss, has a high moisturizing effect, is hypoallergenic and biomimics the skin.

The new natural preservative system… Aspen bark extract – is a natural organic preservative and as such is a unique discovery as it is an effective natural replacement for commonly used harmful chemical preservatives such as the ‘parabens’. It also improves the emollience (the ‘feel-good’ factor) of the cream.

dehydroxanthan gum – is an Eco Certified, non GMO film former, fixative and emulsion stabilizer. It provides unprecedented hold under highly humid conditions without being tacky or flaking.

de-ionized water – this is a pure pharmaceutical grade standard.

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